NAD+ Shows Promise for Parkinson’s & Alzheimer’s

Sparkly_brain.jpgHave you or someone you love been diagnosed with a debilitating degenerative condition such as Parkinson’s Disease (PD), Alzheimer’s Disease (AD), or Multiple Sclerosis (MS)? There are 500,000 cases of Alzheimer’s disease reported each year. Approximately 60,000 Americans are diagnosed with PD each year with more than 10 million people worldwide living with PD. Over one million Americans over the age of 18 are living with multiple sclerosis.

Though these conditions are not necessarily reversible, there are ways to keep symptoms at bay and help the body restore cellular function as well as stopping the progression of symptoms.

Here at SFNM, we offer an IV treatment using Nicotinamide Adenine Dinucleotide (NAD) therapy. NAD+ is a coenzyme found within every cell to help drive enzymatic reactions forward, initiating revitalization of cellular function. In addition, NAD+ also influences healthy gene expression relating to DNA repair, cell death, and certain anti-inflammatory processes.

Why does NAD+ seem to have this positive influence on neurodegenerative conditions?

For starters, every cell in each organ system of the body has a critical role. If this role is not met, the cell cannot properly function within that environment to perform its given purpose. If the DNA structure is damaged or the energy source (mitochondria), isn’t able to be produced, symptoms of disease will begin manifesting in a variety of ways. In particular, neurons are especially susceptible to energy fluctuations due to mitochondrial dysfunction. In turn, damaged neurons can lead to the pathogenesis of various neurodegenerative diseases.

Don't Drink Sugar Calories. Sugary drinks are the most fattening things you can put into your body. This is because liquid sugar calories don't get registered by the brain in the same way as calories from solid foods. For this reason, when you drink soda, you end up eating more total calories. Sugary drinks are strongly associated with obesity, type 2 diabetes, heart disease and all sorts of health problems. Keep in mind that fruit juices are almost as bad as soda in this regard. They contain just as much sugar, and the small amounts of antioxidants do NOT negate the harmful effects of the sugar.

NAD+ has the ability to regulate a class of proteins known as sirtuins. Sirtuins play a vital role in regulating anti-inflammatory processes throughout the body and the brain. Many studies have linked the neuroprotective effects of sirtuins and its implications to AS, PD, MS, as well as ALS.

NAD+ and Parkinson’s Disease

It has also been noted that NAD+ levels fluctuate in patients suffering with PD, therefore, altering the expression of sirtuins. Increased production or administering of NAD+ has been shown to promote neurogenesis (growth and development of new neurons).

There have also been studies done revealing information regarding another class of enzymes that play a key role in DNA repair. These are called PARP—poly (ADP-Ribose) polymerase. While these enzymes are crucial for cell health, they place a heavy tax on mitochondria by depleting levels of NAD+. In the case of excessive oxidative stress and DNA damage, programmed cell death is initiated by lack of NAD+.If you or someone you know is suffering from a degenerative nervous system condition, call SFNM today where a customized protocol and treatment plan will be put together for you!

Cut down on processed food. Processed foods are not good because (1) most nutritional value is lost in the making of these foods and (2) the added preservatives are bad for our health. Many processed foods contain a high amount of salt content, which leads to higher blood pressure and heart disease. Processed foods are anything that is not in its raw form. In general, most food in supermarkets are processed — the more ingredients it has on the label (especially the ones ending with ‘ite’ or ‘ate’), the more processed they are. Watch out for those with salt/sugar in the first 5 ingredients and go for unprocessed food as much as possible.

The following abstracts show the research behind NAD+ for these neurodegenerative conditions:1. Therapeutic Approach to PD2. Mitochondrial Metabolism for PD3. Stroke Recovery with NAD4. NADH As Treatment for AD5. AD Therapy Targeting MitochondriaJillian+mini.pngDr. Jillian Shannon has a general naturopathic practice and specializes in regenerative medicine including BHRT, joint injections and IV therapies. She has been working closely with other practitioners specializing in functional endocrinology and anti-aging medicine with the use of stem cells, ozone, and PRP. She is available full time at SFNM and is accepting new patients.