Boosting NAD+ might turn back our biological clock

Boosting NAD+ might turn back our biological clock

As our body ages, a core clock repressor, PER2, increases and dampens the activity of our circadian rhythms through repressing BMAL1.The level of NAD+ regulates the degradation of PER2, which in turn promotes the activity of BMAL1, keeping the internal clock ticking at a healthy pace.

Nicotinamide mononucleotide ameliorates the depression-like behaviors and is associated with attenuating the disruption of mitochondrial bioenergetics in depressed mice

Nicotinamide mononucleotide ameliorates the depression-like behaviors and is associated with attenuating the disruption of mitochondrial bioenergetics in depressed mice

Transcriptome and metabolome analyses revealed that in depressed mice, NMN reduced the mRNA expression of genes involved in fatty acid synthesis, stimulation of β-oxidation and glycolysis, and increased production of acetyl-coenzyme A for the tricarboxylic acid cycle.

A Simple Trick to Lose Weight and Prevent Diabetes

A Simple Trick to Lose Weight and Prevent Diabetes

A recent study, which took place at the Harvard T.H. Chan School of Public Health in Boston, Massachusetts, found that consumption of propionate, a preservative frequently added to foods, may be associated with an increased risk of obesity and diabetes.

Common food additive could raise the risk of diabetes and obesity

Common food additive could raise the risk of diabetes and obesity

Natural Health News — A food ingredient widely used in baked goods, animal feeds and artificial flavourings, appears to increase levels of several hormones that are associated with risk of obesity and diabetes, according to new research.

Can This Antioxidant Protect You From Liver Disease?

Can This Antioxidant Protect You From Liver Disease?

The researchers found that the mice fed the high fat diet gave birth to offspring with an increased risk of getting NAFLD. The PQQ supplementation in those fed the high fat diet did not influence their weight gain, but it reduced the fat and inflammation in their livers even prior to birth.

Fiber and gut health: Study links low-fiber diet with leaky gut

Fiber and gut health: Study links low-fiber diet with leaky gut

Another thing that the researchers found out was that all of the mice that were fed the low-fiber WSD diet showed a lower rate of gut mucous growth compared with the ones who were fed the standard control diet.

Food Emulsifiers Health Risks

Food Emulsifiers Health Risks

Food Emulsifiers May Affect Brain and Behavior Previous research has shown that adding the food emulsifiers CMC and P80 to the diet leads to low-grade inflammation, obesity and metabolic abnormalities in mice, while disturbing gut microbiota .

Gut bacteria use fiber to improve heart health in mice

Gut bacteria use fiber to improve heart health in mice

Turns out, a particular gut bacteria seems to use fiber to reduce atherosclerosis and inflammation in mice. Mice with Roseburia who ate a high-fiber diet suffered less atherosclerosis and inflammation. The findings: A particular fatty acid, butyrate, is the mechanism through which a high-fiber diet protects the heart in mice.

Mannose Health Benefits

Mannose Health Benefits

Now, research out of Scotland suggests a type of sugar called mannose, found in cranberries and other fruits, may be useful in the treatment of certain cancers.

Can Tetrahydrocannabinol (THC) Help Reduce Alzheimer's?

Can Tetrahydrocannabinol (THC) Help Reduce Alzheimer's?

Tetrahydrocannabinol (THC), the compound responsible for marijuana’s psychoactive effects, may offer hope for treating Alzheimer’s disease, at least according to a study on mice.1 Rodents with a disease similar to Alzheimer’s were given a synthetic form of THC, which resulted in fewer lost brain cells, 20 percent less sticky plaques in the brain (which are linked to Alzheimer’s) as well as a boost in memory.

Does Obesity Cause Arthritis?

Does Obesity Cause Arthritis?

The researchers were surprised to find the effects of obesity on gut bacteria, inflammation and OA were prevented when the high-fat diet was supplemented with oligofructose.

Cannabis 'could reverse ageing process' after THC found to improve memory and learning in older mice

Cannabis 'could reverse ageing process' after THC found to improve memory and learning in older mice

The chemical in cannabis that makes people feel ‘high’ appears to improve learning and memory in older mice, a new study has found – with similar tests on humans planned for later this year.

Probiotics found to mitigate the effects of salt on blood pressure

Probiotics found to mitigate the effects of salt on blood pressure

Since the researchers were able to know that the HSD reduces the number of Lactobacillus murinus, they found that the effect could be counteracted simply by using supplemental probiotics.