The objective of this quasi-experimental study was to determine whether bolus vitamin D3 supplementation taken during or just before COVID-19 was effective in improving survival among frail elderly nursing-home residents with COVID-19.
Now, a team of French scientists has carried out a randomized study showing for the first time ever that a combination of magnesium and vitamin B6 administered to people with severe stress and magnesium deficiency works better than magnesium supplementation alone.
(Yu et al., 2020 | Nature Immunology) The folds of the inner mitochondrial membrane (i.e., cristae) are increased in T lymphocytes present in normal spleens compared to tumors, indicating that the tumor microenvironment caused T cell mitochondrial dysfunction.
A long-term clinical study from Denmark showed that increased nicotinamide adenine dinucleotide (NAD+) content and improved mitochondrial function induced by nicotinamide riboside (NR) supplementation in mouse skeletal muscle does not translate into humans.
“Scientists have been researching the potential health benefits of lipoic acid supplements for decades, including how it might enhance healthy aging and mitigate cardiovascular disease,” said Alexander Michels, another Linus Pauling Institute scientist involved with the study.
(Xie et al., 2020 | Journal of Affective Disorders) NMN supplementation improves body weight to normal in mice with stress hormone-induced depressive symptoms.“Our findings indicate that NMN supplementation can effectively enhance SIRT3 activity to improve mitochondrial energy metabolism in the hippocampus and liver, thereby mitigating [corticosterone]-induced depression-like behavior in mice,” stated the researchers in their study.
The six-week trial, published on April 22 in The American Journal of Clinical Nutrition, showed that NR increased markers for skeletal muscle NAD+ metabolism, affected skeletal muscle metabolism, induced body composition change and raised the sleeping metabolic rate.
Transcriptome and metabolome analyses revealed that in depressed mice, NMN reduced the mRNA expression of genes involved in fatty acid synthesis, stimulation of β-oxidation and glycolysis, and increased production of acetyl-coenzyme A for the tricarboxylic acid cycle.
Dr Bernard Corfe, Senior Lecturer in Molecular Gastroenterology at the University of Sheffield and Principal Investigator for the trial, said: “All participants achieved adequate levels of vitamin D after just 21 days of using an oral spray, with those individuals who were considered severely deficient at the beginning of the trial (with levels lower than 25(OH)D) experiencing the most effective uptake of the supplement.”.
Based on their findings, the researchers concluded that myo-inositol supplementation decreases the expression of fructolytic or lipogenic genes and proteins, as well as TG accumulation in high fructose-induced fatty liver in rats.
Research shows that supplementing with berberine regulates blood sugar levels by promoting insulin sensitivity – which is also good for the heart.Taking omega-3 supplements reduces inflammation in the body, promotes a regular menstrual cycle, reduces androgen levels, and helps with weight loss.
Numerous researchers studied the potential of chlorella as a health supplement for patients with fibromyalgia.The VCU and Ryutzu Keizai research showed that taking chlorella can alleviate pain and fatigue in fibromyalgia patients, as well as healthy people.
Taking a probiotic supplement at the right moment ensures that most of the good bacteria reach your gut for maximum effectiveness. It found that good bacteria, consumed 30 minutes before eating any food, have a higher chance of survival than those taken half an hour later when the stomach is releasing more acid to digest a meal.
Krill oil is a marine oil that is known for providing animal-based omega-3 fats , antioxidants and beneficial substances known as phospholipids 2 , 3 – this last item is particularly important, as it plays a significant role in the absorption of these nutrients (more about this later).
At the same time, the effect of increased oxidative stress in the brain is not well studied, thus researchers at Swinburne University and Austin Hospital in Melbourne (backed by supplement manufacturers Blackmores) conducted a small randomised controlled trial to assess the direct impact of six months of high-dose B vitamin supplementation on brain health and levels of homocysteine and other biomarkers in the brain.
1 , 2 Vitamin K1, which is derived from green plants, is best known for the role it plays in blood clotting, while vitamin K2, derived primarily from fermented foods and animal products such as eggs, meat and liver, 3 is important to hormone production and utilization, as well as bone and heart health.
Glycine Upregulates NADPH and Has Anticancer Activity According to the featured paper, 6 supplemental glycine may be useful for the “prevention and control of atherosclerosis, heart failure , angiogenesis associated with cancer or retinal disorders and a range of inflammation-driven syndromes, including metabolic syndrome.” Glycine may also be an excellent complement to spirulina, as both suppress NOX.
1 The following nutrient deficiency is a powerful predictor of heart disease; recent research shows even subclinical deficiency of this nutrient can compromise your cardiovascular health. Magnesium Low magnesium is a powerful predictor of heart disease, and recent research shows even subclinical magnesium deficiency can compromise your cardiovascular health.
Promotes Thicker, Stronger Hair Like we said hemp oil is packed with nutrients. Each of these nutrients adds a sleekness and shine to your hair that you just don’t get with other oil based cosmetics.
The goal of this study was to answer the question: “What combination of (non-fried) fish intake and omega-3 supplement use is associated with a cardioprotective Omega-3 Index level (i.e., 8 percent or above)?” according to lead researcher Kristina Harris Jackson, a registered dietician who has a doctorate in nutritional sciences.
Nutrition Business Journal's 2018 Global Supplement Business Report provides a collection of data tables and charts broken down by region and country, paired with insight from industry leaders. The report includes more than 100 data charts and 14 company profiles that will provide industry perspective and future insights.
As explained by Dr. Qi Dai, professor of medicine at Vanderbilt University Medical Center and the lead author of this study, “Magnesium deficiency shuts down the vitamin D synthesis and metabolism pathway.” What’s more, magnesium was found to have a regulating effect, raising and lowering vitamin D based on baseline levels.
2. Ward OffCancer In addition to boosting your body’s energy levels and immunity, multivitamins may be particularly useful in the quest to ward off the “Big C.” According to a study published in The Journal of the American Medical Association , taking a daily multivitamin may be a powerful method to reduce your cancer risk.
Impressive scientific research has shown that curcumin , a unique antioxidant compound found in the root of the turmeric plant, is one of the most powerful, natural brain-supporting substances ever discovered! It continues to amaze scientists who study the effects of nutrition on the brain with its remarkable effects on cognitive health.
By avoiding gadgets an hour before bed, your body can produce the melatonin needed to help you sleep at your intended time. A group of researchers found that increasing the melatonin levels of fibromyalgia sufferers through supplementation helped alleviate their symptoms and improved sleep quality.
“Despite a lack of change in mood or cognition outcomes, the present study adds to a growing number of studies suggesting that long-chain (LC) omega-3 PUFA supplementation can influence brain functions at least in part by enhancing cerebrovascular function, which may potentially delay future cognitive decline.”
While research shows other benefits, here I’ll focus on two fundamental conditions that supplementing with NAC can affect: oxidative stress and chronic inflammation. If you have Hashimoto’s or any other autoimmune disease – or if you have chronic inflammation and oxidative stress – you may wish to consider taking this supplement.
In the video above, Chris Kresser, an acupuncturist, licensed integrative medicine clinician and codirector of the California Center for Functional Medicine, interviews11 Lucy Mailing, a microbiome researcher, about two recent studies12,13 that have thrown a bit of a wrench into the standard recommendation to reseed your gut with probiotics after taking a course of antibiotics.
With the increase in HGH levels, you may begin to both look and feel younger with fewer wrinkles, reduced age spots, increased metabolism, improved energy, and a healthier immune system.
Supplementing with saffron (Crocus sativus) can boost athletic performance and recovery, according to a study published in the Journal of Dietary Supplements. These findings of the study suggest that 10 days of supplementation with saffron significantly improved athletic performance.