The six-week trial, published on April 22 in The American Journal of Clinical Nutrition, showed that NR increased markers for skeletal muscle NAD+ metabolism, affected skeletal muscle metabolism, induced body composition change and raised the sleeping metabolic rate.
Transcriptome and metabolome analyses revealed that in depressed mice, NMN reduced the mRNA expression of genes involved in fatty acid synthesis, stimulation of β-oxidation and glycolysis, and increased production of acetyl-coenzyme A for the tricarboxylic acid cycle.
Based on their findings, the researchers concluded that myo-inositol supplementation decreases the expression of fructolytic or lipogenic genes and proteins, as well as TG accumulation in high fructose-induced fatty liver in rats.
Numerous researchers studied the potential of chlorella as a health supplement for patients with fibromyalgia.The VCU and Ryutzu Keizai research showed that taking chlorella can alleviate pain and fatigue in fibromyalgia patients, as well as healthy people.
Taking a probiotic supplement at the right moment ensures that most of the good bacteria reach your gut for maximum effectiveness. It found that good bacteria, consumed 30 minutes before eating any food, have a higher chance of survival than those taken half an hour later when the stomach is releasing more acid to digest a meal.
Krill oil is a marine oil that is known for providing animal-based omega-3 fats , antioxidants and beneficial substances known as phospholipids 2 , 3 – this last item is particularly important, as it plays a significant role in the absorption of these nutrients (more about this later).
At the same time, the effect of increased oxidative stress in the brain is not well studied, thus researchers at Swinburne University and Austin Hospital in Melbourne (backed by supplement manufacturers Blackmores) conducted a small randomised controlled trial to assess the direct impact of six months of high-dose B vitamin supplementation on brain health and levels of homocysteine and other biomarkers in the brain.
1 , 2 Vitamin K1, which is derived from green plants, is best known for the role it plays in blood clotting, while vitamin K2, derived primarily from fermented foods and animal products such as eggs, meat and liver, 3 is important to hormone production and utilization, as well as bone and heart health.
Glycine Upregulates NADPH and Has Anticancer Activity According to the featured paper, 6 supplemental glycine may be useful for the “prevention and control of atherosclerosis, heart failure , angiogenesis associated with cancer or retinal disorders and a range of inflammation-driven syndromes, including metabolic syndrome.” Glycine may also be an excellent complement to spirulina, as both suppress NOX.
The goal of this study was to answer the question: “What combination of (non-fried) fish intake and omega-3 supplement use is associated with a cardioprotective Omega-3 Index level (i.e., 8 percent or above)?” according to lead researcher Kristina Harris Jackson, a registered dietician who has a doctorate in nutritional sciences.
As explained by Dr. Qi Dai, professor of medicine at Vanderbilt University Medical Center and the lead author of this study, “Magnesium deficiency shuts down the vitamin D synthesis and metabolism pathway.” What’s more, magnesium was found to have a regulating effect, raising and lowering vitamin D based on baseline levels.
2. Ward OffCancer In addition to boosting your body’s energy levels and immunity, multivitamins may be particularly useful in the quest to ward off the “Big C.” According to a study published in The Journal of the American Medical Association , taking a daily multivitamin may be a powerful method to reduce your cancer risk.
By avoiding gadgets an hour before bed, your body can produce the melatonin needed to help you sleep at your intended time. A group of researchers found that increasing the melatonin levels of fibromyalgia sufferers through supplementation helped alleviate their symptoms and improved sleep quality.
“Despite a lack of change in mood or cognition outcomes, the present study adds to a growing number of studies suggesting that long-chain (LC) omega-3 PUFA supplementation can influence brain functions at least in part by enhancing cerebrovascular function, which may potentially delay future cognitive decline.”
In the video above, Chris Kresser, an acupuncturist, licensed integrative medicine clinician and codirector of the California Center for Functional Medicine, interviews11 Lucy Mailing, a microbiome researcher, about two recent studies12,13 that have thrown a bit of a wrench into the standard recommendation to reseed your gut with probiotics after taking a course of antibiotics.
Supplementing with saffron (Crocus sativus) can boost athletic performance and recovery, according to a study published in the Journal of Dietary Supplements. These findings of the study suggest that 10 days of supplementation with saffron significantly improved athletic performance.
On the other hand, certain diseases, including diabetes, gastrointestinal ailments and heart failure, bring with them an increased risk of vitamin B1 deficiency.
Like Cannell before them, the researchers believe vitamin D offers protection by increasing antimicrobial peptides in your lungs, and that "[t]his may be one reason why colds and flus are most common in the winter, when sunlight exposure (and therefore the body's natural vitamin D production) is at its lowest …"23