Study Shows Multivitamin Use, But Not Cocoa, Prevents Cognitive Decline

Study Shows Multivitamin Use, But Not Cocoa, Prevents Cognitive Decline

A news article crossed my desk recently that shows that a simple, inexpensive and preventative approach to health shows clear benefits in reducing the risk of cognitive decline and dementia—taking a daily multivitamin-mineral (MVM) supplement.

Investigating the anti-hypertensive effects of pumpkin seed oil

Investigating the anti-hypertensive effects of pumpkin seed oil

Based on these findings, the researchers concluded that regular PSO supplementation can help reduce hypertension and cardiovascular disease risk in postmenopausal women.THE EFFECTS OF PUMPKIN SEED OIL SUPPLEMENTATION ON ARTERIAL HEMODYNAMICS, STIFFNESS AND CARDIAC AUTONOMIC FUNCTION IN POSTMENOPAUSAL WOMEN , 2019 Nov;37:23-26.

Vitamin D and survival in COVID-19 patients: A quasi-experimental study

Vitamin D and survival in COVID-19 patients: A quasi-experimental study

The objective of this quasi-experimental study was to determine whether bolus vitamin D3 supplementation taken during or just before COVID-19 was effective in improving survival among frail elderly nursing-home residents with COVID-19.

Magnesium combined with vitamin B6 has a better effect on severe stress than magnesium supplements alone

Magnesium combined with vitamin B6 has a better effect on severe stress than magnesium supplements alone

Now, a team of French scientists has carried out a randomized study showing for the first time ever that a combination of magnesium and vitamin B6 administered to people with severe stress and magnesium deficiency works better than magnesium supplementation alone.

NR Can Enhance T Cell Antitumor Immunity by Restoring Mitochondrial Function

NR Can Enhance T Cell Antitumor Immunity by Restoring Mitochondrial Function

(Yu et al., 2020 | Nature Immunology) The folds of the inner mitochondrial membrane (i.e., cristae) are increased in T lymphocytes present in normal spleens compared to tumors, indicating that the tumor microenvironment caused T cell mitochondrial dysfunction.

NR Does Not Improve Mitochondrial Function or NAD+ Content in Human Skeletal Muscle After Long-Term Administration

NR Does Not Improve Mitochondrial Function or NAD+ Content in Human Skeletal Muscle After Long-Term Administration

A long-term clinical study from Denmark showed that increased nicotinamide adenine dinucleotide (NAD+) content and improved mitochondrial function induced by nicotinamide riboside (NR) supplementation in mouse skeletal muscle does not translate into humans.

Lipoic acid supplements help some obese people lose weight

Lipoic acid supplements help some obese people lose weight

“Scientists have been researching the potential health benefits of lipoic acid supplements for decades, including how it might enhance healthy aging and mitigate cardiovascular disease,” said Alexander Michels, another Linus Pauling Institute scientist involved with the study.

NMN improves depression symptoms

NMN improves depression symptoms

(Xie et al., 2020 | Journal of Affective Disorders) NMN supplementation improves body weight to normal in mice with stress hormone-induced depressive symptoms.“Our findings indicate that NMN supplementation can effectively enhance SIRT3 activity to improve mitochondrial energy metabolism in the hippocampus and liver, thereby mitigating [corticosterone]-induced depression-like behavior in mice,” stated the researchers in their study.

NR supplementation shows an improvement of body composition in clinical trial

NR supplementation shows an improvement of body composition in clinical trial

The six-week trial, published on April 22 in The American Journal of Clinical Nutrition, showed that NR increased markers for skeletal muscle NAD+ metabolism, affected skeletal muscle metabolism, induced body composition change and raised the sleeping metabolic rate.

Nicotinamide mononucleotide ameliorates the depression-like behaviors and is associated with attenuating the disruption of mitochondrial bioenergetics in depressed mice

Nicotinamide mononucleotide ameliorates the depression-like behaviors and is associated with attenuating the disruption of mitochondrial bioenergetics in depressed mice

Transcriptome and metabolome analyses revealed that in depressed mice, NMN reduced the mRNA expression of genes involved in fatty acid synthesis, stimulation of β-oxidation and glycolysis, and increased production of acetyl-coenzyme A for the tricarboxylic acid cycle.

Supplementation with myo-inositol found to decrease triglyceride buildup in fructose-induced fatty liver

Supplementation with myo-inositol found to decrease triglyceride buildup in fructose-induced fatty liver

Based on their findings, the researchers concluded that myo-inositol supplementation decreases the expression of fructolytic or lipogenic genes and proteins, as well as TG accumulation in high fructose-induced fatty liver in rats.

Chlorella and fibromyalgia: Study confirms relief for your symptoms

Chlorella and fibromyalgia: Study confirms relief for your symptoms

Numerous researchers studied the potential of chlorella as a health supplement for patients with fibromyalgia.The VCU and Ryutzu Keizai research showed that taking chlorella can alleviate pain and fatigue in fibromyalgia patients, as well as healthy people.

Making the most of your probiotic supplement: When you should take it for the best effect

Making the most of your probiotic supplement: When you should take it for the best effect

Taking a probiotic supplement at the right moment ensures that most of the good bacteria reach your gut for maximum effectiveness. It found that good bacteria, consumed 30 minutes before eating any food, have a higher chance of survival than those taken half an hour later when the stomach is releasing more acid to digest a meal.

Krill Oil: Benefits and Uses

Krill Oil: Benefits and Uses

Krill oil is a marine oil that is known for providing animal-based omega-3 fats , antioxidants and beneficial substances known as phospholipids 2 , 3 – this last item is particularly important, as it plays a significant role in the absorption of these nutrients (more about this later).

Get more B vitamins to protect your brain

Get more B vitamins to protect your brain

At the same time, the effect of increased oxidative stress in the brain is not well studied, thus researchers at Swinburne University and Austin Hospital in Melbourne (backed by supplement manufacturers Blackmores) conducted a small randomised controlled trial to assess the direct impact of six months of high-dose B vitamin supplementation on brain health and levels of homocysteine and other biomarkers in the brain.

What Are the Health Benefits of Vitamin K2?

What Are the Health Benefits of Vitamin K2?

1 , 2 Vitamin K1, which is derived from green plants, is best known for the role it plays in blood clotting, while vitamin K2, derived primarily from fermented foods and animal products such as eggs, meat and liver, 3 is important to hormone production and utilization, as well as bone and heart health.

What Is NADPH and NOX?

What Is NADPH and NOX?

Glycine Upregulates NADPH and Has Anticancer Activity According to the featured paper, 6 supplemental glycine may be useful for the “prevention and control of atherosclerosis, heart failure , angiogenesis associated with cancer or retinal disorders and a range of inflammation-driven syndromes, including metabolic syndrome.” Glycine may also be an excellent complement to spirulina, as both suppress NOX.

Study: More fish consumption and omega-3 supplementation needed

Study: More fish consumption and omega-3 supplementation needed

The goal of this study was to answer the question: “What combination of (non-fried) fish intake and omega-3 supplement use is associated with a cardioprotective Omega-3 Index level (i.e., 8 percent or above)?” according to lead researcher Kristina Harris Jackson, a registered dietician who has a doctorate in nutritional sciences.

Top Reasons to Make Magnesium a Priority

Top Reasons to Make Magnesium a Priority

As explained by Dr. Qi Dai, professor of medicine at Vanderbilt University Medical Center and the lead author of this study, “Magnesium deficiency shuts down the vitamin D synthesis and metabolism pathway.” What’s more, magnesium was found to have a regulating effect, raising and lowering vitamin D based on baseline levels.

7 Scientifically Backed Reasons You Should Take a Multivitamin

7 Scientifically Backed Reasons You Should Take a Multivitamin

2. Ward OffCancer In addition to boosting your body’s energy levels and immunity, multivitamins may be particularly useful in the quest to ward off the “Big C.” According to a study published in The Journal of the American Medical Association , taking a daily multivitamin may be a powerful method to reduce your cancer risk.

Melatonin: Benefits and Uses

Melatonin: Benefits and Uses

By avoiding gadgets an hour before bed, your body can produce the melatonin needed to help you sleep at your intended time. A group of researchers found that increasing the melatonin levels of fibromyalgia sufferers through supplementation helped alleviate their symptoms and improved sleep quality.

Brain benefits with long-chain DHA/EPA fatty acids

Brain benefits with long-chain DHA/EPA fatty acids

“Despite a lack of change in mood or cognition outcomes, the present study adds to a growing number of studies suggesting that long-chain (LC) omega-3 PUFA supplementation can influence brain functions at least in part by enhancing cerebrovascular function, which may potentially delay future cognitive decline.”​

Should You Take Probiotics if You Must Take Antibiotics?

Should You Take Probiotics if You Must Take Antibiotics?

In the video above, Chris Kresser, an acupuncturist, licensed integrative medicine clinician and codirector of the California Center for Functional Medicine, interviews11 Lucy Mailing, a microbiome researcher, about two recent studies12,13 that have thrown a bit of a wrench into the standard recommendation to reseed your gut with probiotics after taking a course of antibiotics.

Saffron can enhance performance in athletes

Saffron can enhance performance in athletes

Supplementing with saffron (Crocus sativus) can boost athletic performance and recovery, according to a study published in the Journal of Dietary Supplements. These findings of the study suggest that 10 days of supplementation with saffron significantly improved athletic performance.

What Are the Benefits of Vitamin B1, Thiamine?

What Are the Benefits of Vitamin B1, Thiamine?

On the other hand, certain diseases, including diabetes, gastrointestinal ailments and heart failure, bring with them an increased risk of vitamin B1 deficiency.

Best Nutrients for Cold and Flu Season

Best Nutrients for Cold and Flu Season

Like Cannell before them, the researchers believe vitamin D offers protection by increasing antimicrobial peptides in your lungs, and that "[t]his may be one reason why colds and flus are most common in the winter, when sunlight exposure (and therefore the body's natural vitamin D production) is at its lowest …"23